Compare · Melanotan-1 vs PT-141
Melanotan-1 vs PT-141
Quick answer
They differ in chemistry and reported molecular targets: Melanotan-1 is associated with MC1R (selective), while PT-141 is associated with MC1R. This page compares them only as research materials.
Researchers frequently look up Melanotan-1 and PT-141 side by side. This reference compares the two as laboratory research materials, covering their chemistry, reported molecular targets, and the study areas each appears in. It does not rank them and makes no claim that either is preferable for any purpose; both are described strictly as research materials.
At a glance
Melanotan-1 is research peptide studied mainly in the context of melanogenesis research and pigmentation models. PT-141 is research peptide associated with melanocortin-receptor research and neuroendocrine signaling models.
Both fall within Blueprint Labs' Aesthetic & Looksmaxxing category, which is why they are often researched together or in sequence.
Melanotan-1: chemistry & targets
Melanotan-1 (Afamelanotide) is characterized in the literature by MC1R (selective).
- Class
- research peptide
- Category
- Aesthetic & Looksmaxxing
- Molecular weight
- 1646.86 g/mol
- CAS number
- 75921-69-6
- Primary target
- MC1R (selective)
- Physical form
- Lyophilized powder
PT-141: chemistry & targets
PT-141 (Bremelanotide) is characterized in the literature by MC1R, MC3R, and MC4R (melanocortin receptor agonist).
- Class
- research peptide
- Category
- Aesthetic & Looksmaxxing
- Molecular weight
- 1025.18 g/mol
- CAS number
- 189691-06-3
- Primary target
- MC1R
- Physical form
- Lyophilized powder
How researchers choose between them
Selection in a research setting comes down to the model system and the question being asked: which molecular target is under study, which assays are planned, and how the compound is handled and reconstituted. This is a matter of experimental design, not of one compound being "better."
Melanotan-1 is available from Blueprint Labs as a third-party-tested research material with a certificate of analysis. For research use only. Not for human consumption, diagnostic, or therapeutic use.
Available from Blueprint Labs
Melanotan-1 10mg
Melanotan-1 is available from Blueprint Labs as a third-party-tested research material with a certificate of analysis.
Questions, answered
What's the difference between Melanotan-1 and PT-141?
They differ in chemistry and reported molecular targets: Melanotan-1 is associated with MC1R (selective), while PT-141 is associated with MC1R. This page compares them only as research materials.
Are Melanotan-1 and PT-141 studied together?
They share the Aesthetic & Looksmaxxing research category and are sometimes referenced in adjacent literature, but any pairing is an experimental-design decision, not a recommendation.
Which one is better?
Neither is "better." They are distinct research compounds with different targets, and this reference makes no efficacy, safety, or suitability claim. For research use only. Not for human consumption, diagnostic, or therapeutic use.